| 18:10 | Twins | Chris Paddack | 0-3 6.45 | @ | Guardians | Tanner Bibee | 2-2 5.19 | ||
| 18:35 | Yankees | Carlos Rodón | 3-3 3.50 | @ | Orioles | Kyle Gibson | 0-0 0.00 | ||
| 18:40 | Cubs | Shota Imanaga | 2-1 3.18 | @ | Pirates | Andrew Heaney | 2-1 1.72 | ||
| Cardinals | @ | Reds | Postponed | ||||||
| 18:45 | Nationals | MacKenzie Gore | 2-3 3.34 | @ | Phillies | Zack Wheeler | 2-1 3.62 | ||
| 19:05 | Royals | Michael Lorenzen | 2-3 3.90 | @ | Rays | Taj Bradley | 2-1 5.08 | ||
| 19:07 | Red Sox | Garrett Crochet | 2-2 1.95 | @ | Blue Jays | Bowden Francis | 2-3 3.58 | ||
| 19:10 | Diamondbacks | Eduardo Rodriguez | 1-2 4.40 | @ | Mets | David Peterson | 1-1 3.29 | ||
| 19:40 | Brewers | Freddy Peralta | 2-2 2.43 | @ | White Sox | Tyler Gilbert | 1-1 5.87 | ||
| 20:05 | Athletics | Jacob Lopez | 0-0 0.00 | @ | Rangers | Jacob deGrom | 0-1 3.33 | ||
| 20:10 | Tigers | Reese Olson | 3-1 3.29 | @ | Astros | Ryan Gusto | 3-1 2.78 | ||
| 20:40 | Braves | AJ Smith-Shawver | 0-2 4.61 | @ | Rockies | Germán Márquez | 0-4 9.30 | ||
| 21:40 | Angels | Jack Kochanowicz | 1-3 5.47 | @ | Mariners | Bryce Miller | 1-3 4.21 | ||
| 21:40 | Giants | Logan Webb | 3-1 1.98 | @ | Padres | Nick Pivetta | 4-1 1.20 | ||
| 22:10 | Marlins | Sandy Alcantara | 2-2 6.56 | @ | Dodgers | Noah Davis | 0-1 10.12 |